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Adam E Snook Selected Research

uroguanylin

1/2022A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer.
1/2020Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity.
9/2016Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer.
11/2013Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.

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Adam E Snook Research Topics

Disease

57Neoplasms (Cancer)
12/2022 - 06/2007
39Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 06/2007
12Carcinogenesis
01/2022 - 04/2009
8Colonic Neoplasms (Colon Cancer)
01/2022 - 02/2009
8Neoplasm Metastasis (Metastasis)
01/2019 - 07/2008
5Gastrointestinal Neoplasms (Gastrointestinal Cancer)
12/2022 - 01/2019
3Obesity
01/2021 - 01/2016
3Infections
01/2020 - 04/2008
2Melanoma (Melanoma, Malignant)
01/2022 - 07/2014
2Pseudoxanthoma Elasticum (Gronblad Strandberg Syndrome)
01/2022 - 01/2019
2Adenoma (Adenomas)
01/2020 - 01/2019
2Microsatellite Instability
01/2019 - 01/2018
2Lung Neoplasms (Lung Cancer)
03/2017 - 01/2016
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2017 - 01/2016
2Diarrhea
10/2016 - 01/2010
2Breast Neoplasms (Breast Cancer)
07/2014 - 04/2014
1Weight Loss (Weight Reduction)
01/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2021
1Disease Progression
01/2021
1Parkinson Disease (Parkinson's Disease)
01/2021
1Carcinoma (Carcinomatosis)
01/2020
1Arterial calcification of infancy
01/2019
1Hematologic Neoplasms (Hematological Malignancy)
01/2019
1Hyperphagia (Overeating)
09/2016
1Prostatic Neoplasms (Prostate Cancer)
07/2015
1Cytokine Release Syndrome
11/2014
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
11/2013

Drug/Important Bio-Agent (IBA)

22AntigensIBA
06/2022 - 06/2007
21Enterotoxin ReceptorsIBA
01/2022 - 06/2007
16VaccinesIBA
06/2022 - 07/2008
12Hormones (Hormone)IBA
01/2021 - 09/2013
10Biomarkers (Surrogate Marker)IBA
01/2022 - 06/2007
7guanylinIBA
01/2022 - 11/2013
6Proteins (Proteins, Gene)FDA Link
01/2022 - 07/2008
6Cancer VaccinesIBA
01/2022 - 05/2013
5Chimeric Antigen ReceptorsIBA
12/2022 - 12/2011
5LigandsIBA
01/2022 - 09/2013
5Guanylate Cyclase (Guanylyl Cyclase)IBA
10/2021 - 10/2016
5AutoantigensIBA
01/2020 - 04/2009
4EpitopesIBA
01/2022 - 05/2012
4Immune Checkpoint InhibitorsIBA
01/2022 - 01/2018
4uroguanylinIBA
01/2022 - 11/2013
3DNA (Deoxyribonucleic Acid)IBA
01/2022 - 07/2015
3linaclotideIBA
01/2021 - 01/2016
3Guanylate Cyclase-Coupled ReceptorsIBA
01/2021 - 01/2010
3CytokinesIBA
01/2018 - 04/2008
2Phenobarbital (Luminal)FDA Link
01/2022 - 01/2016
2diphosphoric acid (pyrophosphoric acid)IBA
01/2022 - 01/2019
2CateninsIBA
01/2022 - 01/2020
2plecanatideIBA
01/2021 - 01/2017
2Peptides (Polypeptides)IBA
01/2020 - 10/2016
2Plasma GasesIBA
10/2019 - 01/2018
2Small Interfering RNA (siRNA)IBA
03/2017 - 01/2016
2Interleukin-2 (IL2)IBA
12/2008 - 04/2008
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2022
1Pharmaceutical PreparationsIBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Transcription Factors (Transcription Factor)IBA
01/2022
1Monoclonal AntibodiesIBA
01/2021
1LeptinIBA
01/2021
1Sildenafil Citrate (Viagra)FDA Link
01/2021
1AntibodiesIBA
01/2020
1Neutralizing AntibodiesIBA
01/2020
1NitrogenIBA
10/2019
1Oxygen (Dioxygen)IBA
10/2019
1axicabtagene ciloleucelIBA
01/2019
1tisagenlecleucelIBA
01/2019
1Calcibiotic Root Canal SealerIBA
01/2019
1Surface Antigens (Surface Antigen)IBA
01/2019
1Single-Chain AntibodiesIBA
01/2018
1CarcinogensIBA
12/2017
1Erlotinib Hydrochloride (CP 358,774)FDA Link
03/2017
1A-Form DNA (A-DNA)IBA
01/2017
1Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
10/2016
1Cyclic GMPIBA
10/2016
1Enterotoxins (Enterotoxin)IBA
10/2016
1Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA
10/2016
1AdipokinesIBA
09/2016
1Cell Surface ReceptorsIBA
01/2016
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
07/2015
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2014
1Messenger RNA (mRNA)IBA
11/2014
1Immunotoxins (Immunotoxin)IBA
10/2014
1ClathrinIBA
10/2014
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
07/2014
1Eflornithine (Ornidyl)FDA Link
03/2014
1PolyaminesIBA
03/2014
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
03/2014
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
11/2013

Therapy/Procedure

28Therapeutics
12/2022 - 02/2009
26Immunotherapy
12/2022 - 06/2007
5Drug Therapy (Chemotherapy)
12/2022 - 02/2013
4Radiotherapy
12/2022 - 02/2013
3Chemoprevention
01/2021 - 12/2017
1Lasers (Laser)
01/2021
1Precision Medicine
01/2021
1Intramuscular Injections
01/2019
1Adjuvant Chemotherapy
12/2016
1Hormone Replacement Therapy (Therapy, Hormone Replacement)
11/2014
1Neoadjuvant Therapy
03/2014